Assessing the benefits of rosiglitazone in women with polycystic ovary syndrome through its effects on insulin-like growth factor 1, insulin-like growth factor-binding protein-3 and insulin resistance: a pilot study
نویسندگان
چکیده
José Gomes Batista, José Maria Soares-Jr, Carla Cristina Maganhin, Ricardo Santos Simões, Geraldez Tomaz, Edmund Chada Baracat I Federal University of São Paulo (UNIFESP), Gynecology Department, São Paulo/SP, Brazil. II Federal University of Paraı́ba (UFPB), Obstetrics and Gynecology Department, João Pessoa/PB, Brazil. III Hospital das Clı́nicas da Faculdade de Medicina da Universidade de São Paulo, Gynecology Department, São Paulo/SP, Brazil.
منابع مشابه
The Effect of 8 Weeks Resistance Training With Low Load and High Load on Testosterone, Insulin-like Growth Factor-1, Insulin-like Growth Factor Binding Protein-3 Levels, and Functional Adaptations in Older Women
Objectives The loss of muscle mass in older adults is attributed to the impaired ability of the skeletal muscle in response to anabolic stimuli and the increased activation of the proteolytic signaling pathway. With increasing age, plasma concentrations of circulating anabolic hormones and growth factors, e.g. testosterone, Insulin-like Growth Factor-1 (IGF-1) and Insulin-like Growth Factor Bin...
متن کاملSpecial Considerations on Insulin Resistance Induced Hyperandrogenemia in Women with Polycystic Ovaries Syndrome: A Prominent COVID-19 Risk Factor
Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) infecting mechanism depends on hosting angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) as essential components and androgens as regulators for inducing the expression of these components. Therefore, hyperandrogenism-related disease such as polycystic ovary syndrome (PCOS) in insulin resistant wome...
متن کاملغلظت سرمی روی (Zn) و ارتباط آن با سطح انسولین سرم در زنان مبتلا به سندرم تخمدان پلی کیستیک
Background & objective: Polycystic ovary syndrome is the most common endocrine disorder and main cause of infertility due to anovulation in reproductive aged women.With regard to the important role of insulin resistance and hyperinsulinemia in the pathophysiology of this syndrome and the role of zinc in structure and function of insulin hormone, as zinc dishomeostasis has adverse effect on the ...
متن کاملBrain-derived neurotrophic factor, insulin-like growth factor-I and its binding protein responses to a session of endurance exercise in healthy elderly men
Purpose: This study investigated the effect of endurance activity on brain-derived neurotrophic factor(BDNF), insulin-like growth factor 1(IGF-1) and its binding protein 3(IGFBP-3) in elderly healthy individuals. Materials and Methods: Eleven healthy old males (mean age of 68 ± 2.31 years old, height of 177 ± 3.1 cm and weight of 79 ± 1.5 kg) were studied. Seventy two hours after maxi...
متن کاملInvestigation on the Levels of IGF-I Receptor and IGF-I Binding Protein I in the Brain of Insulin Resistant Rats
Abstract Introduction: There is limited knowledge available on the metabolism of glucose in the brain, an insulin insensitive organ. Insulin receptors hybridize with insulin like growth factor receptor (IGF-I) to transduce the signals in different areas of the brain. In this article we aimed at investigating whether the expression of IGF-I receptor and IGF-I binding proteins (IGFBP1) is change...
متن کامل